CleanFlash CPAP Machine Cleaners - Most Complete CPAP Cleaner Reviews For 2021

Continuous Positive Airway Pressure (CPAP) therapy is one of the most popular treatment options for patients who are suffering from the sleep disorder obstructive sleep apnea. During CPAP therapy, patients use CPAP machines to help keep their airways open, and relieve them of their breathing problems during sleep.

Why Do You Need a CPAP Cleaner?

Using a CPAP machine is generally safe, but not cleaning your equipment before use may put you at risk for health complications from inhaling germs, bacteria, mold, dust, and other particles. Some of these complications may include sinus infection, meningitis, skin problems, nosebleeds, teeth or gum damage, and reactive airway disease. This is also why it is recommended to use a high-quality CPAP cleaner, so you can get rid of bacteria and viruses that soap and water may not be able to remove.

Best CPAP Cleaner Reviews

If you or someone you love are diagnosed with sleep apnea and you’re looking for the best CPAP cleaner for your CPAP machine, you’ve come to the right place. We’ve compiled the best CPAP cleaner reviews to help you decide which device to purchase.

1. CleanFlash® CPAP/BiPAP Machine Cleaner

    Price: $99 (with UV bag)

    CleanFlash® offers one of the most affordable sleep apnea machine cleaners in the market, yet it uses both ozone and UV light for 2 times the cleaning efficiency of a regular CPAP cleaner. This CPAP/BiPAP machine cleaner is safe, registered in FDA, FCC and CE, and also has a two-year warranty. The package comes with an ozone cleaner, a universal hose adapter, a rechargeable li-ion battery, and a UV bag. It’s lightweight and portable, doesn’t contain harmful chemicals, and is 100% automated.

    CleanFlash® CPAP/BiPAP Machine Cleaner is easy to use. You just have to connect the cleaner to the hose and put it into the UV bag. Then, put your CPAP machine, mask and tube inside, press the start button on the ozone cleaner and the UV bag, wait for less than 30 minutes, and you’re good to go. Also, it doesn’t require you to change cartridges.

    CleanFlash CPAP Machine Cleaner- CPAP Cleaners Review

    Top Features
      • Double cleaning power: Ozone + UV light
      • Very affordable
      • Portable and lightweight
      • With two-year warranty
      • FDA, FCC and CE registered
      • Comes with a universal hose adapter
      • Easy to use, just click the start/stop button
      • No harmful chemicals
      • Worldwide shipping
     Product Specifications
      • Dimensions: 120 x 65 x 38 mm
      • Weight: 200g
      • Rechargeable Battery: built-in 2200mAh
      • Charging Type: USB, 5pin, 5V = 1A
      • Automatic Timer: 30mins activation / 5mins cool down
      • Voltage: DC3.7V
      • Store Environment: -20ºC to 55ºC
      • Operation Environment: -5ºC to 40ºC
      • Operation Enclosure Space: <5m³ in enclosed environment
      • Waterproof: IPX1

      2. LEEL Portable CPAP Cleaner and Sanitizer Bundle

      Price: $119

      LEEL’s portable CPAP cleaner and sanitizer bundle is one of the smallest and the latest CPAP sanitizers in the market, so you can easily carry it anywhere. It uses activated oxygen to kill 99.99% of bacteria in your CPAP/BiPAP machine. It has a 2600mAh that can cater to about eight cleaning cycles. It’s also fast charging, and comes with a sanitizing bag and a hose adapter. You can easily use this CPAP cleaner by clicking just one button.

      LEEL Portable CPAP Cleaner and Santizer Bundle - O3

      Top Features
        • Compact and easy to carry
        • Kills 99.99% of bacteria
        • Good battery life
        • Fast charging
        • Easy-to-use, just click one button

      Product Specifications

        • Dimensions: 4.7 x 1.95 x 1.95 in
        • Weight: 7.4 ounces
        • Battery: 2600mAh, 8-12 sanitizing cycles per charge
        • Battery Recharge: 2-2.5hrs
        • Operation: 20min or 30min (preset) options

      3. Clyn 6901 – 2-in-1 UV-C CPAP Sanitizer and Dryer

      Price: $249

      You can use Clyn’s UV-C CPAP sanitizer and dryer in three ways: dry for 45 minutes, sanitize for 15 minutes, and automatically both dry and sanitize for one hour. This equipment is ozone-free, and uses strong UV-C light to kill 99.99% of mold, bacteria and viruses that may be lurking around your CPAP machine. This package may be quite pricier and comes with only a one-year warranty, but it has a large holding capacity which means you can clean several machines at the same time. It comes with a digital touch screen so you can easily use it like your smartphone.

      Clyn 6901 - 2-in-1 UV-C CPAP Sanitizer and Dryer

      Top Features

        • With 3 modes of use
        • Large holding capacity
        • Kills 99.99% of viruses and bacteria
        • Has a digital touch screen
        • With one-year warranty
        • 30-day free return

       Product Specifications

        • Dimensions: 11 x 11 x 9.6 in
        • Weight: 4.5 lbs
        • Operation: Dry (45mins), Sanitize (15mins), Automatic Dry and Sanitize (60mins)
        • Power Rating: Dry – 75W, Sanitize – 8W
        • Voltage: 110V 60Hz
        • Capacity: 7L
        • Store Environment: 0º to 120ºF
        • Operation Environment: 20º to 100ºF

      4. Sleep8 CPAP Cleaning Companion

      Price: $199

      The Sleep8 CPAP Cleaning Companion System is ideal for sanitizing APAP, BIPAP and CPAP machines. It uses an easy-to-pack, large filter bag where you can insert and clean all your machines at once. It also comes with a micro USB charger, a universal adapter, and a one-year warranty. When using the Sleep8 CPAP cleaner, all you have to do is to press start, and the device will automatically turn on, and start cleaning your equipment. The company recommends patients who use this daily to change their bags every three months.

      Sleep8 CPAP Cleaning Companion

      Top Features
        • Large filter bag can fit multiple equipment
        • Virtually silent
        • Easy-to-use, just press start
        • With one-year warranty
        • Travel-friendly

      Product Specifications

        • Dimensions: 5.25 x 3.25 x 2.25 in
        • Weight: 0.58 lbs
        • Power: 100-240VAC, 50/60Hz battery
        • Power Consumption: 4W max
        • AC Power Cord Length: 3ft approx.
        • Rechargeable Battery: Li-Ion, 2200mAh

      5. PurePAP™ CPAP Sanitizer

      Price: $99.95

      PurePAP™ CPAP Sanitizer is another affordable yet portable, high-quality CPAP cleaner. This ultra-quiet device produces activated oxygen to thoroughly clean every corner of your CPAP machine and accessories. To use the PurePAP™ CPAP Sanitizer, you just have to plug in your CPAP machine to the cleaner, turn the cleaner on, and wait for the device to clean your equipment within 30 minutes.

      Just like the others, this CPAP cleaner claims to kill 99.99% of disease-causing pathogens that may be starting to form in your CPAP machine, mask and tubing. It has a rechargeable lithium ion battery that live for up to 10 years. Its batter can be charged in two hours, and can live for about six cleaning cycles.

      PurePAP CPAP Sanitizer

      Top Features
        • Very quiet
        • Affordable
        • Kills 99.99% of viruses, bacteria and odor
        • Good battery life
        • Fast charging time (2 hours)
        • Small and portable
        • Full money back guarantee

      Product Specifications:

        • Package Weight: 1.6 lbs
        • Power Consumption: 5W max
        • Battery: Li-Ion, 2500mAh
        • Adapter Input: AC 100-240V, 50/60Hz
        • Adapter Output: 5V
        • Store Environment: 32ºF to 131ºF
        • Operating Temperature: 50ºF to 100ºF
        • Air Flow: 5.06CFM
        • Operating Cycle: 20-40mins

      6. 3B Lumin LM3000 CPAP Cleaner

      Price: $269

      This CPAP cleaner is ideal for CPAP therapy at home as it uses the same germicidal UVC light that surgical centers and operating rooms use to kill mold, bacteria, fungus and viruses. What we like most about this equipment is that you can use it to sterilize drawer-sized items such as hearing aids, toothbrushes, children’s toys, and more.

      With just one touch, Lumin’s CPAP cleaner can sanitize your CPAP machine and other equipment in as fast as five minutes. Once the cleaning cycle is complete, the device automatically shuts off. This device is low-maintenance, and doesn’t contain any filter to replace.

      3B Lumin LM3000 CPAP Cleaner

      Top Features

        • Uses UVC light for cleaning
        • Fast cleaning cycle (only 5 minutes)
        • Easy-to-use
        • With one-year warranty
        • No maintenance required

       Product Specifications

        • Dimensions: 12.2 x 8.5 x 7.75 in
        • Weight: 5.5 lbs
        • Drawer Dimensions: 9.25 x 6.25 x 5 in, 231 cu in
        • Power: 110VAC 60Hz, 220VAC 50Hz
        • Store Environment: 0º to 120ºF
        • Operating Temperature: 20º to 100ºF
        • Humidity: Up to 93% non-condensing

      7. SoClean 2 – SC1200-SB

      Price: $298

      The SoClean 2 CPAP cleaner automatically cleans CPAP machines using activated oxygen. Just like the other cleaners, SoClean 2 is also easy-to-use. You can simply place your CPAP machine and accessories inside this CPAP cleaner, close the lid, and the device will do the cleaning in about two hours. This product is compatible to major CPAP machine brands, and it contains three adapters to fit to most types of CPAP equipment. It has hose insertions on both sides (left and right), and has an easy filter cartridge system. The company offers this product with a 30-day risk free trial, and a two-year warranty.

      SC1200-SB - SoClean 2

      Top Features

        • Compatible with most CPAP machines
        • Easy-to-use
        • With two-year warranty
        • 30-day risk free trial

       Product Specifications

        • Dimensions: 7.875 x 7.25 x 8.875 in
        • Weight: 7 lbs
        • Power Cord Length: 4ft 8in
        • Store Environment: 10ºC to 50ºC
        • Operating Temperatures: 10Cº to 50ºC
        • Humidity: Up to 95%
        • Power Consumption: 12VDC
        • Frequency Response: 0.48MHz


      8. Sani Bot D6

      Price: $348.74

      The Sani Bot D6 is the largest CPAP cleaner in the company’s range. It uses the transducer generated ultrasound, disinfectant tablets and water for more powerful cleaning. It can also fit your CPAP machine, mask, and tubing so you can clean them all at the same time. The device has a touch screen control panel, an internal water heater, and a one to 30-minute programmable timer. The best thing about it is it comes with 90-day money back guarantee and a one-year manufacturer’s warranty.

      Sani Bot D6

      Top Features

        • Can accommodate mask and hose in the same cleaning cycle
        • With touch screen control panel
        • Easy-to-use
        • With two-year warranty
        • 90-day money back guarantee

       Product Specifications

        • Dimensions: 12.7 x 8.1 x 3.9 in
        • Tank Capacity: 6L
        • Power: 110-120VAC
        • Operating Temperature: Up to 140ºF

      9. VC-2250 – VirtuCLEAN 2.0 by VirtuOx 

      Price: $269

      The VirtuCLEAN is a portable and quiet automatic cleaning device that can kill bacteria, germs and viruses in your CPAP machine, mask and tubing in as fast as 30 minutes. It doesn’t require any maintenance, hose adapters, soap or any cleaning solution. It comes with a rechargeable lithium ion battery LCD display with a reminder feature, and completes charging time in about two hours. The company offers this product with a two-year warranty and a 30-day risk free trial period.

      You can use it by connecting one end of your CPAP tube to the cleaning device, and the other end of the tube to the sanitizing bag. Next, put your CPAP humidifier chamber and mask inside the sanitizing bag, and wait for 30 minutes.

      VC-2250 - VirtuCLEAN 2.0 by VirtuOx

      Top Features

        • Quiet and portable
        • No hose adapters required
        • Easy-to-use
        • No maintenance needed
        • With two-year warranty
        • 30-day risk free trial

      Product Specifications

        • Dimensions: 4.5in diameter x 1.7in height
        • Weight: 0.5lbs
        • Battery: Rechargeable Li-Ion LCD display with count down timer
        • Charging Time: 2 hours, 4-5 sanitizing cycles

      10. Motif Medical Clean-Z CPAP Ozone Sanitizer

      Price: $149

      As its name suggests, Motif Medical’s Clean-Z Ozone Sanitizer uses activated oxygen or ozone in removing bacteria, mold, and germs in your CPAP machine and accessories. This portable device is tested to be 99.99% effective in killing harmful microorganisms. The sanitizer pack comes with a USB-powered adapter, two tubing adapters (22mm and 15mm), a carbon air filter that needs to be replaced every six months, and a sanitizer bag. Clean-Z is available with a one-year warranty.

      Motif Medical Clean-Z CPAP Ozone Sanitizer

      Top Features

        • Laboratory tested to be 99.99% effective in killing bacteria and viruses
        • With one-year warranty
        • Comes with USB power adapter
        • Fits 22mm and 15mm hoses

      Product Specifications

        • Dimensions: 4.1 x 2.4 x 1.6 in
        • Weight: Less than 5 ounces
        • Power Supply: 4.5-6.5VDC
        • Power Consumption: 10W
        • Store Environment: -4º to 131ºF
        • Operating Temperatures: 23º to 113ºF
        • Air Flow: 3.5CFM

      11. NUWAVE® Plus CPAP Sanitizer

      Price: $299

      The NUWAVE® Plus CPAP Sanitizer uses ozone as its main cleaning agent. This device has a large zippered sanitizing bag or chamber where you can clean your CPAP machine and accessories at once, and has a cleaning time of about 30 minutes. With a 2,600mAh rechargeable lithium ion battery, you can finish 8-9 sanitizing cycles before the next recharge.

      To use this CPAP cleaner, you must put your CPAP machine and water humidifier in the sanitation bag, and then zip it. Next, you should connect the tubing to the generator and then to the universal fitting on the sanitation bag. After that, just press the button on the ozone generator for more or less two seconds to start the cleaning process. The company offers free shipping, and a two-year warranty.

      Nuwave Plus CPAP Sanitizer

      Top Features

        • Has a zippered sanitizing bag
        • Kills 99.99% of viruses and bacteria
        • With two-year warranty
        • Free shipping

      Product Specifications

        • Dimensions: 4.875 x 2.375 x 2 in
        • Weight: 0.45 lbs
        • Battery: Rechargeable Li-Ion, 2600maAh 3.7V
        • Charging: 4 hours, 8-9 sanitizing cycles
        • Power Supply: 120VAC input, 5VDC 1000mA output
        • Store Environment: -20ºC to 25ºC
        • Operating Temperature: 0º to 45ºC

      12. Purify O3 Portable Ozone CPAP/BiPAP Sanitizer

      Price: $199

      This CPAP cleaner also uses ozone as its cleaning aid. It provides a hospital-grade sanitation process that kills 99.99% of bacterial and viruses in your CPAP equipment. As a maintenance-free device, the Purify O3 Portable Ozone CPAP/BiPAP Sanitizer requires no filters, cleaning solutions and replacement bags. It only takes one push button to start the cleaning cycle which normally finishes in 35 minutes. Also, it’s FDA-registered, is quiet, and is portable enough for easy travel and packing.

      Purify O3 Portable Ozone CPAP-BiPAP Sanitizer

      Top Features

        • Very quiet
        • Lightweight and portable
        • Easy-to-use
        • FDA-registered
        • With two-year warranty

      Product Specifications

        • Dimensions: 4.5 x 2.75 x 2 in
        • Weight: 0.5 lbs
        • Power Source: 4W Rechargeable Li-Ion battery
        • Operating Temperatures: 23ºF to 113ºF

      13. PrimeClean Plus CPAP Cleaner

      Price: $109.99

      This CPAP cleaner also uses activated oxygen, or ozone, to eliminate 99.9 percent of germs, without introducing moisture that could become a breeding ground for more germs. It only requires 30 minutes of cleaning. This portable cleaner runs on a lithium-ion battery, making it suitable for travel. Each full charge allows 4 cleaning cycles. Recharging the battery can be done within two hours and only needs a USB port through an electrical outlet using the provided USB adapter.

      PrimeClean Plus CPAP Cleaner

      Top Features

        • Portable and light-weight, only weighs 8 ounces
        • 10-year battery life
        • Ultra quiet
        • Kills 99.9% of germs and bacteria
        • Uses activated oxygen to disinfect
        • Comes with 1-year warranty

      Product Specifications

        • Dimensions: 4.6 x 2.4 in
        • Weight: 0.5 lbs
        • Battery: Rechargeable Li-Ion
        • Charging Time: 2 hours, 3 sanitizing cycles

      14. Zopec Medical Portable UVC and Ozone CPAP Cleaner

      Price: $99.99

      Ultraviolet (UV) light is known to kill harmful bacteria, viruses, fungus, and mold. This CPAP cleaner uses far-ultraviolet (UVC) in the 180-280nm wavelengths. With 60-minute cycle time, this cleaner also boasts to kill 99.99% of viruses and bacteria. Though it’s light and portable, weighs only 2.8lbs, this device has larger capacity for disinfecting larger items.

      CPAP1000 Portable UVC and Ozone CPAP Cleaner

      Top Features

        • One of the largest-capacity CPAP cleaners, despite of ultra-light weight
        • Requires virtually no maintenance with no filters to replace and a UVC light bulb that’s designed to outlast the device itself
        • Features one-button operation
        • Kills 99.99% of viruses and bacteria
        • Comes with 1-year warranty

      Product Specifications

        • Dimensions: 11 x 9 x 6 in
        • Weight: 2.8 lbs
        • Power Consumption: 5W

      15. iSonic P4381 – Ultrasonic CPAP Cleaner

      Price: $289.95

      Ultrasonic technology produces cavitation, or millions of air bubbles, which implode and dislodge debris from the items submerged in water. This CPAP cleaner deep cleans CPAP masks and hoses inside and out. It comes with a stainless weight bracket which holds down the mask and the hose from floating.

      To use, remove the plastic basket, add lukewarm water up to the “max line” indicated, add 2 iSonic cleaning tablets, fully submerge the mask and the hose inside the tank, place the bracket, set the timer to 5-10 minutes.

      iSonic P4831 - Ultrasonic CPAP Cleaner

      Top Features

        • Uses ultrasonic technology for deep cleaning of CPAP masks and hoses
        • Has a touch-sensing control panel
        • Comes with 48 cleaning tablets to kill bacteria and remove odor
        • Can fit a 6-foot long hose
        • 1-year warranty

      Product Specifications

        • Dimensions: 17.5 x 10.8 x 8.1 in
        • Tank Dimensions: 9.8 x 6.9 x 3.1 in
        • Tank Capacity: 3L
        • Operating Temperatures: Up to 140ºF
        • Power: 100-120VAC or 220-240VAC, 180W
        • Temperature Rating: Ambient 15º to 25ºC



      We hope this list of CPAP cleaner reviews has helped you decide which CPAP cleaner to purchase based on your budget, cleaning agent preference and more. The CPAP cleaners mentioned here are just some of the many equipment being offered both online and in retail outlets, so if you want another version of this CPAP cleaner reviews list, please feel free to let us know.

      If you’re looking for a top-grade sleep apnea machine cleaner that is affordable, can kill 99.99% of bacteria, germs and molds, is portable, lightweight, and complies with government regulations and medical equipment benchmarks, we recommend that you choose CleanFlash® CPAP/BiPAP Machine Cleaner. For only $99, you can already make the most of its double-powered (using ozone and UV light), fast cleaning process and two-year warranty. Wherever you are in the world, you can purchase and receive the CleanFlash® set that comes with a cleaning device, a UV bag, a charging cord, a USB power adapter, a universal tube adapter, and a detailed manual.

      Finally, to learn more about the CleanFlash® CPAP/BiPAP cleaner set, please visit our frequently asked questions page. For more information about sleep apnea, CPAP therapy, CPAP machines and CPAP cleaners, please feel free to read some of our blog posts.

      Thanks for reading!



      No doubt, we all know that we need to clean our CPAP and BiPAP devices regularly so we don't give germs, bacteria, and viruses any chance to develop. If you're still having second thoughts whether you're good with manual cleaning using mild soap and water, or if you really need an automated CPAP sanitizer, check out below some of the CPAP cleaner reviews from actual CleanFlash® users.